In the fermentation process, due to some improper operations, it is easy to cause foaming in the microbial fermentation process, which will bring some negative effects to the fermentation process. The foam can be defoamed by adding a biological fermentation defoamer. The biological fermentation defoamer is convenient to use and cost-effective. This article analyzes the causes and hazards of foaming in biological fermentation, and proposes a defoamer for biological fermentation.
(Picture: Biological fermentation process)
The cause of foaming in biological fermentation
Biological fermentation foam refers to a discontinuous liquid phase with air or other gases distributed in a continuous liquid phase, or a continuous phase with air or other gases distributed in a continuous liquid phase.
Why does it foam during fermentation? Generally speaking, it can be summarized as the following:
1. The microorganisms in the culture medium are active, the culture medium is rich in raw materials, and the content of organic nitrogen sources is high;
2. The temperature rise and rapid mixing operation result in a large amount of foam;
3. The influence of microbial surrounding environmental factors such as the composition of the fermentation medium, the aeration rate, and the rotation speed will cause foaming.
(Picture: Analysis of the cause of foaming in biological fermentation)
The harm of biological fermentation foam
Appropriate foam for biological fermentation helps the fermentation process, but too much foam is detrimental to the fermentation process. Persistent foam will bring many negative effects on fermentation, mainly in:
1. When the fermentation liquid rises to the top of the tank, it may seep out from the shaft seal, increasing the chance of contamination of bacteria;
2. If there is a large amount of bubbling, failure to control it in time will cause "fluid escape" and result in product loss. Therefore, reasonable control of the foam produced in the fermentation process is one of the factors for achieving high yield;
3. Reduce the loading coefficient of the fermentation tank (liquid volume / fermentation tank volume). The charging coefficient of the fermenter is generally about 0.7, and the foam that fills the remaining space usually accounts for about 10% of the required medium;
4. Increased the non-uniformity of the flora. Due to the changes in the height of the foam and the microorganisms in different growth cycles floating with the foam or sticking to the tank wall, this part of the bacteria sometimes grows in the gas phase environment, thereby affecting the uniformity of the flora.
(Picture: The harm of biological fermentation foam)
Biological fermentation defoaming program
It is difficult to avoid the foam problem in the biological fermentation process, and it can be adjusted by adding defoamers to eliminate excess foam.
The biological fermentation defoamer developed by the Nanhui defoamer manufacturer for the fermentation process is a type of emulsion defoamer. It is biologically inert, does not affect microorganisms, does not affect the fermentation process, and has a good defoaming effect.
(Picture: Nanhui biological fermentation defoamer provides free samples)
Nanhui biological fermentation defoamer has the following advantages:
1. Free samples
Professional technology according to your foaming situation and requirements, recommend samples;
2. Easy to use
It can be directly added to the fermentation broth together with the base material, which is very convenient for defoaming;
3. Stable defoaming
The defoamer has good stability, can withstand high temperature, strong acid and alkali and other environments, and can defoam continuously;
4. High cost performance
The fermentation defoaming agent has a high concentration and a small amount of addition. The general dosage is only about one-thousandth to three-thousandths of the foaming system, which can be tested according to experiments.
Nanhui is a manufacturer with years of application experience. It has far more defoaming technology than other antifoaming agents in the market. From the above cases, we prove the strength of our Nanhui defoamer. We have a group of excellent defoaming engineers, and an independent laboratory that facilitates defoaming experiments with foams that are difficult for customers to solve. If you want to know more about defoamer products, you can call our hotline: +86 13428601010.
This article is from the manufacturer of Nanhui defoamer (http://www.nhdefoamer.com/), please indicate the source if you need to reprint.
